Great TextExpander tip from Systematic episode 3 for inserting different e-mail signatures:

• -= expands to a minimal sign off (e.g. – Rhyd)
• --= expands to a more verbose sign off (e.g. as above but with more contact info)
• -–= expands to my work e-mail signature

TextExpander is one of my favourite apps. 13 hours typing saved so far.